Marmaduke, the world-s most lovable Great Dane, leaps from comic strip fame (appearing in 600 newspapers in over 20 countries) to big screen stardom in this family comedy event. A suburban family moves to a new neighborhood in Orange County, California with their large yet lovable Great Dane, who has a tendency to wreak havoc in his own oblivious way. But its not all living large for the Duke, who finds that fitting in with his new four-legged friends - and a potential romantic interest - isnt always easy for a super-sized teenage dog. Owen Wilson gives the beloved Great Dane his voice in the film, which also features the voices of Fergie, George Lopez, Emma Stone and Kiefer Sutherland.

Marmaduke, the worlds most lovable Great Dane, leaps from comic strip fame (appearing in 600 newspapers in over 20 countries) to big screen stardom in this family comedy event. A suburban family moves to a new neighborhood in Orange County, California with their large yet lovable Great Dane, who has a tendency to wreak havoc in his own oblivious way. But its not all living large for the Duke, who finds that fitting in with his new fourlegged friends and a potential romantic interest isnt always easy for a supersized teenage dog. Owen Wilson gives the beloved Great Dane his voice in the film, which also features the voices of Fergie, George Lopez, Emma Stone and Kiefer Sutherland.

Marmaduke, the world is most lovable Great Dane, leaps from comic strip fame (appearing in 600 newspapers in over 20 countries) to big screen stardom in this family comedy event. A suburban family moves to a new neighborhood in Orange County, California with their large yet lovable Great Dane, who has a tendency to wreak havoc in his own oblivious way. But its not all living large for the Duke, who finds that fitting in with his new fourlegged friends and a potential romantic interest is not always easy for a supersized teenage dog. Owen Wilson gives the beloved Great Dane his voice in the film, which also features the voices of Fergie, George Lopez, Emma Stone and Kiefer Sutherland.

A suburban family moves to a new neighborhood with their large yet lovable Great Dane, who has a tendency to wreak havoc in his own oblivious way.

A suburban family moves to a new neighborhood with their large yet lovable Great Dane, who has a tendency to wreak havoc in his own oblivious way.

Marmaduke, the world s most lovable Great Dane, leaps from comic strip fame (appearing in 600 newspapers in over 20 countries) to big screen stardom in this family comedy event. A suburban family moves to a new neighborhood in Orange County, California with their large yet lovable Great Dane, who has a tendency to wreak havoc in his own oblivious way. But its not all living large for the Duke, who finds that fitting in with his new four-legged friends - and a potential romantic interest - isn t always easy for a super-sized teenage dog. Owen Wilson gives the beloved Great Dane his voice in the film, which also features the voices of Fergie, George Lopez, Emma Stone and Kiefer Sutherland.

Marmaduke, the world s most lovable Great Dane, leaps from comic strip fame (appearing in 600 newspapers in over 20 countries) to big screen stardom in this family comedy event. A suburban family moves to a new neighborhood in Orange County, California with their large yet lovable Great Dane, who has a tendency to wreak havoc in his own oblivious way. But its not all living large for the Duke, who finds that fitting in with his new four-legged friends - and a potential romantic interest - isn t always easy for a super-sized teenage dog. Owen Wilson gives the beloved Great Dane his voice in the film, which also features the voices of Fergie, George Lopez, Emma Stone and Kiefer Sutherland.